Futurism

There’s a Grim New Expression: “AI;DR”

The internet is so overrun with AI that anywhere you go, you run the risk of accidentally stepping into a puddle of slop. If only there were a gallant gentleman always at hand to drape their coat over ...
eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...
CNN

13 controversial redactions from the Epstein files — and what we’re learning about them

This has been a big week in the long-running — and still very much not-over — saga of the Jeffrey Epstein files. That’s because we’ve begun to learn more about the Justice Department’s controversial ...
Nature

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

The development of non-viral gene-transfer technologies that can support stable chromosomal integration and persistent gene expression in vivo is desirable. Here we describe the successful use of ...
Nature

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

Figure 3: hTERT clones undergo normal growth arrest in response to PALA and γ-irradiation. Figure 4: hTERT clones arrest appropriately in response to the spindle inhibitor colcemid. Cells were lysed ...
Kaleido Scope

Forging the future of radiology

We're dedicated to nurturing and guiding the future generation of physicians and physician-scientists, recognizing that our trainees are the cornerstone of our nation's healthcare system.