Scientists from the University of Portsmouth and the University of Manchester say they have developed a fusion enzyme that ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

Clascoterone (cortexolone 17α-propionate) is a first-in-class topical anti-androgen approved in 2020 for the treatment of acne in patients aged 12 years and older. It works by blocking androgen ...

A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule. The anti-cancer molecule salinosporamide A, also called Marizomb, is in Phase III clinical ...

As demand intensifies for "green chemistry" standards across the pharmaceutical and chemical industries, Creative Enzymes—a leading global enzyme technology service provider—today announced the ...

A new study finds enhanced activity of a specific enzyme drives spinocerebellar ataxia type 14, which suggests inhibiting the enzyme may have therapeutic potential. pinocerebellar ataxias are a group ...