Signaling is fundamental to how cells sense and respond to their environment—but in immune cells, those signals must be ...

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Macrophages, the immune system’s front-line scavenger cells, do more than simply digest dead cells. A new study published in ...

Scientists led by Sergey Troyanovsky, Ph.D., professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process ...

Researchers have discovered how mitochondrial stress drives T cell exhaustion and a potential way to restore their ...

The discovery that tissues use electricity to expel unhealthy cells is part of a surge of renewed interest in the currents flowing through our bodies. We’re used to thinking of the brain as an ...