The space between the arachnoid and pia meningeal layers encasing the brain is a landscape of connective tissue, blood vessels, and cerebrospinal fluid. Scientists debate how that fluid moves within ...

The typical signs and symptoms of idiopathic NPH are shown. In a retrospective study involving 418 patients with shunt-responsive idiopathic NPH, 96% of the patients had gait difficulty, 76% had ...

Approximately 400,000 cases of infantile and childhood hydrocephalus occur worldwide annually. 1 For most affected patients, treatment is inadequate because of limited access to care. Left untreated, ...

A major international study has uncovered a new biological clue that could help predict dementia long before memory problems arise. Researchers from the University of Cambridge and Zhejiang University ...

A novel blood and cerebrospinal fluid (CSF) measure showed promise as a biomarker for Parkinsonian disorders. CSF levels of DOPA decarboxylase (DDC) -- an enzyme that converts levodopa into dopamine - ...

Bagged in three layers of meninges and selectively fenced off by the blood brain barrier, our central nervous system (CNS) interacts within strict limits with our immune system. Protective ...

A popular hypothesis for how the brain clears molecular waste, which may help explain why sleep feels refreshing, is a subject of debate. Encased in the skull, perched atop the spine, the brain has a ...

With age, the brain’s ability to clear aggregating proteins such as Aβ wanes. In the November 9 Nature, researchers led by Jonathan Kipnis at Washington University in St. Louis suggest a reason why.