Phthalates are high production volume chemicals used primarily as plasticizers in many industrial and consumer products. As a result of their ubiquitous use, there is documented widespread human ...

A new publication in Nature Reviews Methods Primers provides essential guidance for conducting rigorous systematic reviews on studies with animals and cells. It also highlights the benefits of these ...

When scientists and regulators need clear answers to health risks—such as whether Tylenol causes autism (it doesn’t)—they typically turn to systematic reviews, widely regarded as medicine’s gold ...

Introduction Interstitial lung disease (ILD) is a serious extra-articular manifestation of rheumatoid arthritis (RA) associated with increased morbidity and mortality. The pulmonary safety of biologic ...

Many of our colleagues sought guidance on the process, tools, and expectations for systematic reviews—a methodology increasingly adopted in fields such as biomechanics, communication disorders, ...

This systematic review found that studies of case management interventions have adequate quality and, in many cases, show cost-effective or even cost-saving results. Results: A total of 29 studies ...

The literature on physician-mediated interventions to reduce costs is scant and provides little guidance on effective strategies. Objectives: Provider organizations are increasingly entering ...

Introduction With the rapid ageing of the global population, the number of persons with dementia (PwDs) is increasing, placing substantial psychological and physical burdens on family caregivers.

Introduction A disproportionate share of global neonatal deaths occurs in armed-conflict settings, where progress in reducing neonatal mortality remains slow. This systematic review aims to synthesise ...

This project was supported by Contract EP-C-14-005, Task Order #5, between the National Academy of Sciences and the US Environmental Protection Agency. Any opinions, findings, conclusions, or ...