Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Endosomal and cytosolic nucleic acid receptors sense microbial nucleic acids and initiate innate immune responses. However, in some circumstances their activation by endogenous nucleic acids can also ...

Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

In our bodies, there are trillions of cells. From white blood cells to skin cells, each type has its own specific function which helps us perform tasks and survive. But what makes up these cells and ...

Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches. The structure and chemistry of nucleic acids is ...

Gastrointestinal (GI) cancers remain a major global health burden, accounting for substantial cancer-related morbidity and mortality worldwide. Cell-free ...

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological ...

Nature encodes nucleic acids to assemble enormously complex and highly functional materials that form the foundation of life. To establish a similar code to construct synthetic, unnatural materials ...

At the heart of molecular biology is the study of genetic material – DNA and RNA – which serve as the fundamental blueprints for life. These nucleic acids are not only essential for understanding how ...

The use of the nucleic acid platform for antigen delivery has expanded rapidly in the past decade, highlighted by the ...